Cortical spreading depression-induced preconditioning in the brain
نویسندگان
چکیده
منابع مشابه
The Neuroprotective Effects of Long-Term Repetitive Transcranial Magnetic Stimulation on the Cortical Spreading Depression-induced Damages in Rat’s Brain
Introduction: Cortical Spreading Depression (CSD) is a propagating wave of neural and glial cell depolarization with important role in several clinical disorders. Repetitive Transcranial Magnetic Stimulation (rTMS) is a potential tool with preventive treatment effects in psychiatric and neuronal disorders. In this paper, we study the effects of rTMS on CSD by using behavioral and histological a...
متن کاملCortical Spreading Depression induced Preconditioning in Mouse Neocortex
19 Cortical spreading depression (CSD) is able to confer neuroprotection when 20 delivered at least one day in advance of an ischemic event. However, its 21 ability to confer neuroprotection on a more immediate time frame has not 22 previously been investigated. Here we have used mouse neocortical brain 23 slices to study the effects of repeated episodes of CSD in layer V and layer 24 II/III py...
متن کاملP 23: Apoptosis Following Cortical Spreading Depression in Juvenile Rats
Introduction: Repetitive cortical spreading depression (CSD) can lead to cell death in immature brain tissue. Caspases are involved in neuronal cell death in several CSD-related neurological disorders. Yet, whether repetitive CSD itself can induce caspase activation in adult or juvenile tissue remains unknown. Inducing repetitive CSD in somatosensory cortices of juvenile and adult rats in vivo,...
متن کاملP85: Spreading Depression in the Brain Cortex and Spinal Cord
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متن کاملCortical spreading depression-induced preconditioning in mouse neocortex is lamina specific.
Cortical spreading depression (CSD) is able to confer neuroprotection when delivered at least 1 day in advance of an ischemic event. However, its ability to confer neuroprotection in a more immediate time frame has not previously been investigated. Here we have used mouse neocortical brain slices to study the effects of repeated episodes of CSD in layer V and layer II/III pyramidal neurons. In ...
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ژورنال
عنوان ژورنال: Neural Regeneration Research
سال: 2016
ISSN: 1673-5374
DOI: 10.4103/1673-5374.194759